"This collection already contains an address with scheme http. There can be at most one address per scheme in this collection. If your service is being hosted in IIS you can fix the problem by setting 'system.serviceModel/serviceHostingEnvironment/multipleSiteBindingsEnabled' to true or specifying 'system.serviceModel/serviceHostingEnvironment/baseAddressPrefixFilters'."Reason:The main reason for this exception is due to multiple bindings enabled for the the IIS website under which BizTalk360 is installed. You can check this easily by seeing the right hand side pane as shown below
Solution:If ASP.NET 4.0 is installed on the server, you can change the IIS Application pool to use ASP.NET 4.0.
Restart the Application pool.